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��ƵAPP Institute

The ��ƵAPP Institute

Welcome to the ��ƵAPP Institute, a hub for our latest thinking on how collaborative clinical trial data, technology, and expertise can improve patient lives and inspire the next generation of treatments.

Papers and Publications

2023 Publication

Better Data, Better Decisions: Achieve greater certainty in clinical trial financial management by leveraging adaptive, accurate, and defendable fair market value

2023 Publication

An interpretable data augmentation framework for improving generative modeling of synthetic clinical trial data

2022 Publication

CXCL13 is a predictive biomarker in idiopathic multicentric Castleman disease

2022 Publication

Phase IB Trial Efficacy Estimates via a Clinical Trial Synthetic Control Arm

2021 Publication

Towards an extensible ontology for streaming sensor data for clinical trials

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Presentations and Webinars

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Insights and Perspectives

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Conference Abstracts and Posters

Pooled Clinical Trial Data Analyses Comparing the Biology of HER2-low vs HER2-0 Breast Cancer in Patients with Metastatic Breast Cancer Following Treatment with Standard Single Agent Chemotherapy

Phosphorus disruption is associated with the incidence and severity of neurotoxicity symptoms in CD19-targeted CAR T-cell therapy: a pooled clinical trial analysis

Machine Learning-Based Decision Tree for Identifying and Grading Severity of ICANS Based on Neurological Adverse Events in Patients Treated with CD19 CAR T-Cell

Significant Cytokine Release Syndrome Risk Model With T-Cell Engaging Therapies

Research Hub Framework: Optimizing T-Cell Redirecting Therapies Through Multi-Sector Collaborations and Data

PMSA May 2023 Poster Tree Based Marketing Mix Models

EHA CAR T-cell Meeting: Co-occurrence patterns of CRS and ICANS in patients undergoing autologous CD19-targeted CAR T-cell treatments

Brain Metastases in Patients with KRAS Mutant Advanced NSCLC Receiving Docetaxel: Pooled Clinical Trial Data Analysis

NEALS: CA3 levels in plasma associate strongly with site of onset in ALS

ASCO: Assessment of Vitamin D deficiency and COVID-19 diagnosis in patients with breast or prostate cancer using Electronic Medical Records

ASCO: Oncology Trial Enrollment Trends Following the First Wave of the COVID-19 Pandemic

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